date:Jun 30, 2012
l concentrations owing to inadequate methodology or insufficient reporting,it wrote.
Most of the remaining RCTs were at high risk of bias, owing to methodological limitations in the analysis, and/or had poor reporting of the data, and differences in the results obtained between trials appeared to be unrelated to the dose of ISP used, sample size or study duration.
The NDA said while four RCTs showed a significant cholesterol-lowering effect, 14 did not, and therefore the meta-analysis,would no