date:Sep 17, 2013
found both grape seed proanthocyanidins (GSP) and metformin (MET ) help the insulinresistant rats via different metabolic pathways and suggested use of grape seed proanthocyanidins (GSP)can enhance the efficacy of metformin in treatment of metabolic syndrome.
The study also indicated that a high fat, high fructose diet can cause insulin resistance, a precursor to type2 diabetes mellitus. High fat and high fructose are typical dietary components in the Western diet. Highfructose corn syrup (now