date:May 27, 2013
Alzheimer's disease.
In the study, Sr. John's wort extract with the concentration of hyperforin at 5% was fed to 30 day-oldmale C57BL/6J-APP/PS1+/- mice for 60 or 120 days, respectively. Age-matched mice were fed a dietwithout Sr. John's wort extract supplemented.
The researchers observed that Mice receiving St. John's Wort extract showed (i) significant reductions ofparenchymal beta-amyloid 1-40 and 1-42 accumulation, and (ii) moderate but statistically significantincreases in cerebrovascular