date:Mar 15, 2013
epG2 cells. CPE also enhanced the levels of GLUT-2. Interestingly, EC and CPE modulated the expression of phosphoenolpyruvate carboxykinase, a key protein involved in the gluconeogenesis, leading to a diminished glucose production. In addition, EC- and CPE-regulated hepatic gluconeogenesis was prevented by the blockage of AKT and AMPK.
The researchers said the data suggest that EC and CPE strengthen the insulin signaling by activating key proteins of that pathway and regulating glucose producti