date:Mar 04, 2013
prostate cancertumor bearing mice. Among other things, these MilkThistle compounds were found to inhibit tumorangiogenesis biomarkers CD31 and nestin andsignaling molecules that are needed for angiogenesisincluding VEGF, VEGFR1, VEGFR2, phospho-Aktand HIF-1.
On the other hand, these compounds did not seem tocause any adverse effect on the vessel count innormal tissue in the liver, lung, and kidney of the tumor bearing mice.The researchers concluded Overall, these studies elucidated the compar